Mobility and cognition are associated with wellbeing and health related quality of life among older adults: a cross-sectional analysis of the Vancouver Falls Prevention Cohort.
Identifieur interne : 000E77 ( Main/Exploration ); précédent : 000E76; suivant : 000E78Mobility and cognition are associated with wellbeing and health related quality of life among older adults: a cross-sectional analysis of the Vancouver Falls Prevention Cohort.
Auteurs : Jennifer C. Davis [Canada] ; Stirling Bryan [Canada] ; Linda C. Li [Canada] ; John R. Best [Canada] ; Chun Liang Hsu [Canada] ; Caitlin Gomez [Canada] ; Kelly A. Vertes [Canada] ; Teresa Liu-Ambrose [Canada]Source :
- BMC geriatrics [ 1471-2318 ] ; 2015.
Descripteurs français
- KwdFr :
- Analyse multifactorielle (MeSH), Canada (MeSH), Chutes accidentelles (prévention et contrôle), Cognition (MeSH), Disparités de l'état de santé (MeSH), Femelle (MeSH), Humains (MeSH), Mobilité réduite (MeSH), Mâle (MeSH), Qualité de vie (psychologie), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Vieillissement (physiologie), Vieillissement (psychologie), Équilibre postural (MeSH), Études transversales (MeSH), Évaluation gériatrique (méthodes).
- MESH :
- méthodes : Évaluation gériatrique.
- physiologie : Vieillissement.
- prévention et contrôle : Chutes accidentelles.
- psychologie : Qualité de vie, Vieillissement.
- Analyse multifactorielle, Canada, Cognition, Disparités de l'état de santé, Femelle, Humains, Mobilité réduite, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Équilibre postural, Études transversales.
English descriptors
- KwdEn :
- Accidental Falls (prevention & control), Aged (MeSH), Aged, 80 and over (MeSH), Aging (physiology), Aging (psychology), Canada (MeSH), Cognition (MeSH), Cross-Sectional Studies (MeSH), Female (MeSH), Geriatric Assessment (methods), Health Status Disparities (MeSH), Humans (MeSH), Male (MeSH), Mobility Limitation (MeSH), Multivariate Analysis (MeSH), Postural Balance (MeSH), Quality of Life (psychology).
- MESH :
- methods : Geriatric Assessment.
- physiology : Aging.
- prevention & control : Accidental Falls.
- psychology : Aging, Quality of Life.
- Aged, Aged, 80 and over, Canada, Cognition, Cross-Sectional Studies, Female, Health Status Disparities, Humans, Male, Mobility Limitation, Multivariate Analysis, Postural Balance.
Abstract
BACKGROUND
Ascertaining individuals' quality of life and wellbeing is essential in public health and clinical research. The impact of these two pressing geriatric syndromes--impaired mobility and cognitive function--on wellbeing and quality of life is not well examined. Hence, our objective was to identify key clinically relevant outcome measures of mobility and cognitive function that explain variation in wellbeing and health related quality of life (HRQoL) among community dwelling older adults.
METHODS
We conducted a cross-sectional analysis of 229 participants presenting to the Vancouver Falls Prevention Clinic from June 2010 through October 2013. The linear regression models included two dependent variables: the ICECAP-O assessing wellbeing and the EQ-5D-3L assessing HRQoL. Key independent variables included the Short Performance Physical Battery (SPPB) and the Montreal Cognitive Assessment (MoCA). Covariates included Functional Comorbidity Index (FCI), sex and age. In the two multiple linear regression models, age was statistically controlled. Other covariates (i.e., sex and FCI) were included based on statistical significance (i.e., p < 0.05).
RESULTS
The SPPB was significantly associated with HRQoL and with wellbeing after adjusting for known covariates (p < 0.05, Unstandardized ß (Standard Error) 0.023 (0.006) for HRQoL and 0.016 (0.003) for wellbeing). The MoCA was significantly associated with wellbeing after adjusting for known covariates (p = 0.006), Unstandardized ß (Standard Error) 0.005 (0.002) but not with health related quality of life (p > 0.05).
CONCLUSION
We found that a measure of mobility and balance was associated with HRQoL and wellbeing. However, cognitive function was associated with wellbeing only. This study highlights the potential importance of considering wellbeing as an outcome measure if interventions are intended to have a broader impact than health alone.
DOI: 10.1186/s12877-015-0076-2
PubMed: 26142897
PubMed Central: PMC4491415
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. john.best@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. john.best@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3</wicri:regionArea><wicri:noRegion>V6T 1Z3</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, 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xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. liang.hsu@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. 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caitlin.gomez@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. caitlin.gomez@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation></author><author><name sortKey="Vertes, Kelly A" sort="Vertes, Kelly A" uniqKey="Vertes K" first="Kelly A" last="Vertes">Kelly A. Vertes</name><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. kelly.vertes@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. kelly.vertes@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation></author><author><name sortKey="Liu Ambrose, Teresa" sort="Liu Ambrose, Teresa" uniqKey="Liu Ambrose T" first="Teresa" last="Liu-Ambrose">Teresa Liu-Ambrose</name><affiliation wicri:level="3"><nlm:affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3</wicri:regionArea><wicri:noRegion>V6T 1Z3</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9</wicri:regionArea><wicri:noRegion>V5Z 1 M9</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26142897</idno><idno type="pmid">26142897</idno><idno type="doi">10.1186/s12877-015-0076-2</idno><idno type="pmc">PMC4491415</idno><idno type="wicri:Area/Main/Corpus">000E69</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000E69</idno><idno type="wicri:Area/Main/Curation">000E69</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000E69</idno><idno type="wicri:Area/Main/Exploration">000E69</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Mobility and cognition are associated with wellbeing and health related quality of life among older adults: a cross-sectional analysis of the Vancouver Falls Prevention Cohort.</title><author><name sortKey="Davis, Jennifer C" sort="Davis, Jennifer C" uniqKey="Davis J" first="Jennifer C" last="Davis">Jennifer C. Davis</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Clinical Epidemiology and Evaluation, 828 West 10th Avenue, Vancouver, Canada. jennifer.davis@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre for Clinical Epidemiology and Evaluation, 828 West 10th Avenue, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Vancouver Coastal Health Research Institute (VCHRI), Vancouver, BC, V6T 2B5, Canada. jennifer.davis@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Vancouver Coastal Health Research Institute (VCHRI), Vancouver, BC, V6T 2B5</wicri:regionArea><wicri:noRegion>V6T 2B5</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. jennifer.davis@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation></author><author><name sortKey="Bryan, Stirling" sort="Bryan, Stirling" uniqKey="Bryan S" first="Stirling" last="Bryan">Stirling Bryan</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Clinical Epidemiology and Evaluation, 828 West 10th Avenue, Vancouver, Canada. Stirling.Bryan@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre for Clinical Epidemiology and Evaluation, 828 West 10th Avenue, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Vancouver Coastal Health Research Institute (VCHRI), Vancouver, BC, V6T 2B5, Canada. Stirling.Bryan@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Vancouver Coastal Health Research Institute (VCHRI), Vancouver, BC, V6T 2B5</wicri:regionArea><wicri:noRegion>V6T 2B5</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. Stirling.Bryan@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation></author><author><name sortKey="Li, Linda C" sort="Li, Linda C" uniqKey="Li L" first="Linda C" last="Li">Linda C. Li</name><affiliation wicri:level="3"><nlm:affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. lli@arthritisresearch.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. lli@arthritisresearch.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Arthritis Research Centre of Canada, 5591 No. 3 Road, Richmond, BC, V6X 2C7, Canada. lli@arthritisresearch.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Arthritis Research Centre of Canada, 5591 No. 3 Road, Richmond, BC, V6X 2C7</wicri:regionArea><wicri:noRegion>V6X 2C7</wicri:noRegion></affiliation></author><author><name sortKey="Best, John R" sort="Best, John R" uniqKey="Best J" first="John R" last="Best">John R. Best</name><affiliation wicri:level="3"><nlm:affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. john.best@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. john.best@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. john.best@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. john.best@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3</wicri:regionArea><wicri:noRegion>V6T 1Z3</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9, Canada. john.best@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9</wicri:regionArea><wicri:noRegion>V5Z 1 M9</wicri:noRegion></affiliation></author><author><name sortKey="Hsu, Chun Liang" sort="Hsu, Chun Liang" uniqKey="Hsu C" first="Chun Liang" last="Hsu">Chun Liang Hsu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. liang.hsu@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. liang.hsu@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. liang.hsu@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. liang.hsu@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3</wicri:regionArea><wicri:noRegion>V6T 1Z3</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9, Canada. liang.hsu@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9</wicri:regionArea><wicri:noRegion>V5Z 1 M9</wicri:noRegion></affiliation></author><author><name sortKey="Gomez, Caitlin" sort="Gomez, Caitlin" uniqKey="Gomez C" first="Caitlin" last="Gomez">Caitlin Gomez</name><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. caitlin.gomez@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. caitlin.gomez@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation></author><author><name sortKey="Vertes, Kelly A" sort="Vertes, Kelly A" uniqKey="Vertes K" first="Kelly A" last="Vertes">Kelly A. Vertes</name><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. kelly.vertes@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. kelly.vertes@hiphealth.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation></author><author><name sortKey="Liu Ambrose, Teresa" sort="Liu Ambrose, Teresa" uniqKey="Liu Ambrose T" first="Teresa" last="Liu-Ambrose">Teresa Liu-Ambrose</name><affiliation wicri:level="3"><nlm:affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of British Columbia, Vancouver, BC, V6T 2B5</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3</wicri:regionArea><wicri:noRegion>V6T 1Z3</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9, Canada. tlambrose@exchange.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9</wicri:regionArea><wicri:noRegion>V5Z 1 M9</wicri:noRegion></affiliation></author></analytic><series><title level="j">BMC geriatrics</title><idno type="eISSN">1471-2318</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Accidental Falls (prevention & control)</term><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Aging (physiology)</term><term>Aging (psychology)</term><term>Canada (MeSH)</term><term>Cognition (MeSH)</term><term>Cross-Sectional Studies (MeSH)</term><term>Female (MeSH)</term><term>Geriatric Assessment (methods)</term><term>Health Status Disparities (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Mobility Limitation (MeSH)</term><term>Multivariate Analysis (MeSH)</term><term>Postural Balance (MeSH)</term><term>Quality of Life (psychology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse multifactorielle (MeSH)</term><term>Canada (MeSH)</term><term>Chutes accidentelles (prévention et contrôle)</term><term>Cognition (MeSH)</term><term>Disparités de l'état de santé (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Mobilité réduite (MeSH)</term><term>Mâle (MeSH)</term><term>Qualité de vie (psychologie)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Vieillissement (physiologie)</term><term>Vieillissement (psychologie)</term><term>Équilibre postural (MeSH)</term><term>Études transversales (MeSH)</term><term>Évaluation gériatrique (méthodes)</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Geriatric Assessment</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Évaluation gériatrique</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Vieillissement</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Aging</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Accidental Falls</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Chutes accidentelles</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Qualité de vie</term><term>Vieillissement</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Aging</term><term>Quality of Life</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Canada</term><term>Cognition</term><term>Cross-Sectional Studies</term><term>Female</term><term>Health Status Disparities</term><term>Humans</term><term>Male</term><term>Mobility Limitation</term><term>Multivariate Analysis</term><term>Postural Balance</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse multifactorielle</term><term>Canada</term><term>Cognition</term><term>Disparités de l'état de santé</term><term>Femelle</term><term>Humains</term><term>Mobilité réduite</term><term>Mâle</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Équilibre postural</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Ascertaining individuals' quality of life and wellbeing is essential in public health and clinical research. The impact of these two pressing geriatric syndromes--impaired mobility and cognitive function--on wellbeing and quality of life is not well examined. Hence, our objective was to identify key clinically relevant outcome measures of mobility and cognitive function that explain variation in wellbeing and health related quality of life (HRQoL) among community dwelling older adults.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We conducted a cross-sectional analysis of 229 participants presenting to the Vancouver Falls Prevention Clinic from June 2010 through October 2013. The linear regression models included two dependent variables: the ICECAP-O assessing wellbeing and the EQ-5D-3L assessing HRQoL. Key independent variables included the Short Performance Physical Battery (SPPB) and the Montreal Cognitive Assessment (MoCA). Covariates included Functional Comorbidity Index (FCI), sex and age. In the two multiple linear regression models, age was statistically controlled. Other covariates (i.e., sex and FCI) were included based on statistical significance (i.e., p < 0.05).</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>The SPPB was significantly associated with HRQoL and with wellbeing after adjusting for known covariates (p < 0.05, Unstandardized ß (Standard Error) 0.023 (0.006) for HRQoL and 0.016 (0.003) for wellbeing). The MoCA was significantly associated with wellbeing after adjusting for known covariates (p = 0.006), Unstandardized ß (Standard Error) 0.005 (0.002) but not with health related quality of life (p > 0.05).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>We found that a measure of mobility and balance was associated with HRQoL and wellbeing. However, cognitive function was associated with wellbeing only. This study highlights the potential importance of considering wellbeing as an outcome measure if interventions are intended to have a broader impact than health alone.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">26142897</PMID><DateCompleted><Year>2016</Year><Month>01</Month><Day>25</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>06</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-2318</ISSN><JournalIssue CitedMedium="Internet"><Volume>15</Volume><PubDate><Year>2015</Year><Month>Jul</Month><Day>05</Day></PubDate></JournalIssue><Title>BMC geriatrics</Title><ISOAbbreviation>BMC Geriatr</ISOAbbreviation></Journal><ArticleTitle>Mobility and cognition are associated with wellbeing and health related quality of life among older adults: a cross-sectional analysis of the Vancouver Falls Prevention Cohort.</ArticleTitle><Pagination><MedlinePgn>75</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/s12877-015-0076-2</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Ascertaining individuals' quality of life and wellbeing is essential in public health and clinical research. The impact of these two pressing geriatric syndromes--impaired mobility and cognitive function--on wellbeing and quality of life is not well examined. Hence, our objective was to identify key clinically relevant outcome measures of mobility and cognitive function that explain variation in wellbeing and health related quality of life (HRQoL) among community dwelling older adults.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We conducted a cross-sectional analysis of 229 participants presenting to the Vancouver Falls Prevention Clinic from June 2010 through October 2013. The linear regression models included two dependent variables: the ICECAP-O assessing wellbeing and the EQ-5D-3L assessing HRQoL. Key independent variables included the Short Performance Physical Battery (SPPB) and the Montreal Cognitive Assessment (MoCA). Covariates included Functional Comorbidity Index (FCI), sex and age. In the two multiple linear regression models, age was statistically controlled. Other covariates (i.e., sex and FCI) were included based on statistical significance (i.e., p < 0.05).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The SPPB was significantly associated with HRQoL and with wellbeing after adjusting for known covariates (p < 0.05, Unstandardized ß (Standard Error) 0.023 (0.006) for HRQoL and 0.016 (0.003) for wellbeing). The MoCA was significantly associated with wellbeing after adjusting for known covariates (p = 0.006), Unstandardized ß (Standard Error) 0.005 (0.002) but not with health related quality of life (p > 0.05).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">We found that a measure of mobility and balance was associated with HRQoL and wellbeing. However, cognitive function was associated with wellbeing only. This study highlights the potential importance of considering wellbeing as an outcome measure if interventions are intended to have a broader impact than health alone.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Davis</LastName><ForeName>Jennifer C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Centre for Clinical Epidemiology and Evaluation, 828 West 10th Avenue, Vancouver, Canada. jennifer.davis@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Vancouver Coastal Health Research Institute (VCHRI), Vancouver, BC, V6T 2B5, Canada. jennifer.davis@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. jennifer.davis@ubc.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bryan</LastName><ForeName>Stirling</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Centre for Clinical Epidemiology and Evaluation, 828 West 10th Avenue, Vancouver, Canada. Stirling.Bryan@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Vancouver Coastal Health Research Institute (VCHRI), Vancouver, BC, V6T 2B5, Canada. Stirling.Bryan@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. Stirling.Bryan@ubc.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Linda C</ForeName><Initials>LC</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. lli@arthritisresearch.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. lli@arthritisresearch.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Arthritis Research Centre of Canada, 5591 No. 3 Road, Richmond, BC, V6X 2C7, Canada. lli@arthritisresearch.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Best</LastName><ForeName>John R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. john.best@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. john.best@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. john.best@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. john.best@ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9, Canada. john.best@ubc.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hsu</LastName><ForeName>Chun Liang</ForeName><Initials>CL</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. liang.hsu@hiphealth.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. liang.hsu@hiphealth.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. liang.hsu@hiphealth.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. liang.hsu@hiphealth.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9, Canada. liang.hsu@hiphealth.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gomez</LastName><ForeName>Caitlin</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. caitlin.gomez@hiphealth.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. caitlin.gomez@hiphealth.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vertes</LastName><ForeName>Kelly A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. kelly.vertes@hiphealth.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. kelly.vertes@hiphealth.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu-Ambrose</LastName><ForeName>Teresa</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy, 2177 Wesbrook Mall, Vancouver, Canada. tlambrose@exchange.ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, V6T 2B5, Canada. tlambrose@exchange.ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Aging, Mobility, and Cognitive Neuroscience Lab, 2211 Wesbrook Mall, Vancouver, Canada. tlambrose@exchange.ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Djavad Mowafaghian Centre for Brain Health, University of British Columbia & VCHRI, 2215 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada. tlambrose@exchange.ubc.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Hip Health and Mobility, 311-2647 Willow Street, Vancouver, BC, V5Z 1 M9, Canada. tlambrose@exchange.ubc.ca.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>HERU1</GrantID><Acronym>CSO_</Acronym><Agency>Chief Scientist Office</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MOB-93373</GrantID><Acronym>CAPMC</Acronym><Agency> CIHR</Agency><Country>Canada</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>07</Month><Day>05</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Geriatr</MedlineTA><NlmUniqueID>100968548</NlmUniqueID><ISSNLinking>1471-2318</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000058" MajorTopicYN="N">Accidental Falls</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000375" MajorTopicYN="Y">Aging</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName><QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N">Canada</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003071" MajorTopicYN="Y">Cognition</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015577" MajorTopicYN="N">Geriatric Assessment</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D054624" MajorTopicYN="N">Health Status Disparities</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D051346" MajorTopicYN="Y">Mobility Limitation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015999" MajorTopicYN="N">Multivariate Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004856" MajorTopicYN="N">Postural Balance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011788" MajorTopicYN="N">Quality of Life</DescriptorName><QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>09</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>06</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>7</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>7</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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Li</name><name sortKey="Li, Linda C" sort="Li, Linda C" uniqKey="Li L" first="Linda C" last="Li">Linda C. Li</name><name sortKey="Li, Linda C" sort="Li, Linda C" uniqKey="Li L" first="Linda C" last="Li">Linda C. Li</name><name sortKey="Liu Ambrose, Teresa" sort="Liu Ambrose, Teresa" uniqKey="Liu Ambrose T" first="Teresa" last="Liu-Ambrose">Teresa Liu-Ambrose</name><name sortKey="Liu Ambrose, Teresa" sort="Liu Ambrose, Teresa" uniqKey="Liu Ambrose T" first="Teresa" last="Liu-Ambrose">Teresa Liu-Ambrose</name><name sortKey="Liu Ambrose, Teresa" sort="Liu Ambrose, Teresa" uniqKey="Liu Ambrose T" first="Teresa" last="Liu-Ambrose">Teresa Liu-Ambrose</name><name sortKey="Liu Ambrose, Teresa" sort="Liu Ambrose, Teresa" uniqKey="Liu Ambrose T" first="Teresa" last="Liu-Ambrose">Teresa Liu-Ambrose</name><name sortKey="Liu Ambrose, Teresa" sort="Liu Ambrose, Teresa" uniqKey="Liu Ambrose T" first="Teresa" last="Liu-Ambrose">Teresa Liu-Ambrose</name><name sortKey="Vertes, Kelly A" sort="Vertes, Kelly A" uniqKey="Vertes K" first="Kelly A" last="Vertes">Kelly A. Vertes</name><name sortKey="Vertes, Kelly A" sort="Vertes, Kelly A" uniqKey="Vertes K" first="Kelly A" last="Vertes">Kelly A. 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